Biosynthesis and production technology of the anti obesity agent Tripterygium wilfordii Hook
Tripterygium abstract Obesity is a major health risk, and there is still a lack of effective medication treatment. An effective…
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Efficient exploration of terpenoid biosynthetic gene clusters in filamentous fungi
terpenoid Summary Terpenoid are key components of human medicines and are the largest family of natural products. Fungi are important…
shikimic acid in Escherichia coli systems engineering
Systems engineering of Escherichia coli for highlevel shikimic acid Research background shikimic acid is a common precursor of drugs and…
Autoresistant enzyme-mediated synthesis of purine biosynthesis inhibitors
This study proves that FrzK is a self-resistant enzyme. Through sequence analysis, homology modeling, crystal structure analysis and point mutation,…