What is NAD+?
NAD is one of the most important coenzymes in the human body, also known as coenzyme 1, the full name of nicotinamide adenine dinucleotide (nicotinamide dinucleotide). It is a key substance discovered in the field of human aging inhibition.
Dr. David, winner of the Bell Prize in Medicine, tested NAD+ on mice and found that after a week, the mice returned to the young state of 20 years old!
Studies have found that NMN can increase the level of NAD+ in the human body, and NAD+ will gradually decrease with age, thus unlocking the secret of aging!
Professor David Sinclair of Harvard Medical School found that β-nicotinamide adenine dinucleotide has a good anti-aging effect.
Subsequently, many academic papers on NAD+ were published in authoritative academic journals represented by Cell, Nature, and Science.
Top 10 benefits of NAD+
Let’s take a look at what modern science has discovered about NAD+.
1, anti-aging
NAD+ maintains chemical communication between the nucleus and mitochondria, and weakened communication is an important cause of cellular aging.
NAD+ can remove the increasing error DNA code in the process of cell metabolism, maintain the normal expression of genes, maintain the normal operation of cells, and slow down the aging of human cells.
2, Repair DNA damage
NAD+ is an essential substrate for the DNA repair enzyme PARP and has a significant impact on DNA repair, gene expression, cell development, cell survival, chromosome reconstruction and gene stability.
3, Activating longevity protein
Sirtuins, often referred to as a family of macrobiotic proteins, play important regulatory roles in cellular functions such as inflammation, cell growth, circadian rhythm, energy metabolism, neuronal function, and stress resistance, and NAD+ is an important enzyme in the synthesis of macrobiotic proteins.
Activate all 7 longevity proteins in the human body, and play an important role in the process of cell resistance, energy metabolism, preventing cell variation, apoptosis and senescence.
4, Provide energy
The mitochondria in human cells are the power plants of the cells, and NAD+ is an important coenzyme in the mitochondria that generates the energy molecule ATP, converting nutrients into energy needed by the human body.
5, Promote vascular regeneration and maintain vascular elasticity
Blood vessels are essential tissues for vital activities. With age, blood vessels also gradually lose their softness, harden, thicken, and narrow, causing “arteriosclerosis.”
NAD+ can increase the activity of elastin in blood vessels, thereby maintaining the elasticity of blood vessels and maintaining blood vessel health.
6, Boost metabolism
Metabolism is the sum of various chemical reactions in the body, the body will continue to carry out the exchange of matter and energy, when this exchange stops, the body’s life will also end.
Professor Anthony and his research team at the University of California found that NAD+ can effectively improve the slowing down of cell metabolism associated with aging, thereby improving people’s physical health and extending life span.
7, Protect heart health
The heart is the most important organ in the human body, and the level of NAD+ in the body plays an important role in maintaining the normal operation of the heart.
The reduction of NAD+ may be related to many mechanisms of cardiovascular disease, and a large number of basic studies have also confirmed the effect of NAD+ supplementation on heart disease.
8, Prevention of cardiovascular and cerebrovascular diseases
Studies have shown that almost all seven subtypes of sirtuins (SIRT1-SIRT7) are associated with the development of cardiovascular disease. sirtuins are considered to be an exciting target for the treatment of cardiovascular diseases, especially SIRT1.
NAD+ is the only substrate of Sirtuins. Timely supplementation of NAD+ to the human body can fully activate the activity of various subtypes of Sirtuins, thus playing a role in protecting cardiovascular health and preventing cardiovascular diseases.
9, Promote hair growth
The main cause of hair loss is the loss of vitality of hair blast cells, and the loss of vitality of hair blast cells is because the level of NAD+ in the human body is decreased, and hair blast cells do not have enough ATP to carry out hair protein synthesis, thus losing vitality and causing hair loss.
Supplementing NAD+ can strengthen the trichinic acid cycle and produce ATP, so that the hair mother cell has sufficient capacity to produce hair protein, and thus improve hair loss.
10, Weight management
heavier person will not only affect people’s quality of life and physical condition, but also induce other chronic diseases. Previous studies have shown that NAD+ precursor NMN can reduce the weight of heavier person patients.
In 2017, Professor David Sinclair of Harvard Medical School and a team from the Australian Medical School compared heavier person female mice with treadmill exercise for 9 weeks and daily use of NMNfor 18 days, and found that NMN had a significantly greater effect on liver fat metabolism and synthesis than exercise.
Timely supplement NAD+
With age, the level of NAD+(Coenzyme I) in the body will show a cliff-like decline, which directly leads to body function and cell aging!
After middle age, the level of NAD+ in the body decreases year by year, at the age of 50, the level of β-nicotinamide adenine dinucleotide in the body is only half of that at the age of 20, and by the age of 80, the level of β-nicotinamide adenine dinucleotide is only about 1% of that at the age of 20.
Supplementing NAD+ becomes particularly important. β-nicotinamide adenine dinucleotide can help repair, optimize, and stabilize DNA, which is helpful for neurodegeneration, diabetes, cardiovascular disease, and more.
Exogenous supplement of NAD+ can effectively improve the level of β-nicotinamide adenine dinucleotide in the human body, help the body function and cells to restore vitality, so as to restore the body to a young state and delay aging.
